Arizona’s diverse landscapes, charming desert towns, and rich cultural heritage make it an unforgettable vacation destination. From the iconic red rocks of Sedona to the vibrant energy of Scottsdale, the state offers everything from tranquil retreats to bustling city escapes. Whether you’re seeking a spiritual getaway, adventure-filled excursions, or world-class dining, Arizona has a perfect spot for every type of traveler. Pair that with a wide range of vacation rentals—luxury villas, cozy casitas, and serene desert sanctuaries—and you’re in for a stay that’s as unforgettable as the views. Here are twelve must-see spots with great places to stay.
#1 Sedona
Sedona is famed for its stunning red rock formations, vortex energy sites, and artsy vibe. Whether you’re hiking Cathedral Rock, exploring the Chapel of the Holy Cross, or strolling through Tlaquepaque Arts Village, Sedona offers a peaceful yet inspiring escape. Outdoor enthusiasts will love the scenic trails and Jeep tours, while wellness seekers flock to healing spas and yoga studios. The breathtaking desert scenery and unique spiritual ambiance make Sedona a top destination in Arizona. Sunsets here are particularly magical, lighting up the rocks in vivid hues. Don’t miss the chance to unwind amid Sedona’s mystical and majestic landscape.
#2 Scottsdale
Scottsdale blends desert beauty with urban sophistication. Known for its luxurious resorts, world-class golf courses, and lively arts scene, it’s ideal for travelers who love upscale experiences. Old Town Scottsdale buzzes with art galleries, boutique shopping, and fine dining. You can also explore the stunning Sonoran Desert by ATV or on horseback. For a cultural touch, visit the Scottsdale Museum of Contemporary Art or the historic Western Spirit Museum. Whether you’re into spa retreats or nightlife, Scottsdale has a vibe that caters to all tastes while basking in the golden Arizona sunshine year-round.
#3 Cottonwood
Located in the heart of Arizona’s wine country, Cottonwood is a hidden gem. Nestled near the Verde River and close to Jerome and Sedona, it’s known for its charming Old Town, where you’ll find tasting rooms, antique shops, and local eateries. It’s also a great launchpad for kayaking, hiking, or exploring the nearby Tuzigoot National Monument. The vibe is laid-back yet full of character, perfect for travelers looking for a slower pace with lots of local flavor. Cottonwood offers an authentic Arizona experience with a touch of rustic elegance and scenic beauty.
#4 Jerome
Perched on Cleopatra Hill, Jerome is a quirky former mining town turned artist haven. With its steep streets, haunted hotels, and sweeping valley views, it’s one of Arizona’s most unique destinations. Visitors can explore ghost tours, visit art galleries, or tour the Jerome State Historic Park. The town has an edgy, creative spirit, making it a haven for artists, musicians, and free spirits. Every building tells a story, and the views over Verde Valley are stunning. Jerome is the kind of place where history, eccentricity, and natural beauty come together beautifully.
#5 Prescott
Prescott offers a taste of the Old West with its iconic Whiskey Row, pine forests, and granite dells. It’s a favorite among nature lovers, history buffs, and those craving cooler temperatures. Explore the historic courthouse square, hike through Prescott National Forest, or kayak on Watson Lake. The city hosts events year-round, including art festivals and rodeos. Its charming downtown mixes modern shops with Western saloons, creating a unique blend of past and present. Prescott’s small-town feel and outdoor adventures make it a refreshing break from the desert heat.
#6 Flagstaff
Flagstaff is a mountain town known for its alpine beauty, ski slopes, and proximity to national parks. At over 7,000 feet elevation, it offers cool temps and pine-scented air. It’s home to Northern Arizona University, giving it a youthful, laid-back vibe. Visitors love hiking in the San Francisco Peaks, stargazing at Lowell Observatory, or catching a snowfall in winter. It’s also a gateway to the Grand Canyon and Route 66. Whether you’re chasing snow or summer trails, Flagstaff is a refreshing destination year-round.
#7 Page
Page is your launch point for exploring Arizona’s incredible slot canyons, Lake Powell, and Horseshoe Bend. The town is small but serves as a base for epic natural sights. Antelope Canyon’s swirling sandstone is a photographer’s dream, while boat tours on Lake Powell reveal hidden coves and desert scenery. The contrast of red rocks against turquoise water is stunning. Page is a must for adventurers, nature lovers, and those seeking some of Arizona’s most iconic landscapes. Just be sure to bring your camera—everywhere you look is postcard-worthy.
#8 Tucson
Tucson is a cultural and culinary gem in southern Arizona. Surrounded by five mountain ranges and the vast Saguaro National Park, it’s a paradise for hikers and desert lovers. The city’s Mexican-American heritage infuses its art, architecture, and especially its food—Tucson is a UNESCO City of Gastronomy. Explore historic Mission San Xavier del Bac, hike Sabino Canyon, or catch live music downtown. Tucson’s laid-back, artsy energy makes it a favorite for creative souls and curious minds. Desert sunsets here are especially magical.
#9 Bisbee
Bisbee is a funky, artsy town tucked in Arizona’s Mule Mountains. Once a thriving copper-mining town, it’s now known for its colorful houses, narrow stairways, and bohemian spirit. Explore the Bisbee Mining & Historical Museum, shop for quirky antiques, or attend an underground ghost tour. The town is full of eccentric charm and creative energy, drawing in writers, artists, and travelers seeking something different. It feels part-ghost town, part-living gallery. Every corner reveals a story or an artwork.
#10 Arizona Sanctuary Experiences (Sedona Area)
For those craving true peace and reconnection, Arizona Sanctuary Experiences near Sedona offers a high-end spiritual escape. This secluded retreat combines eco-conscious design with luxury amenities. Set amid red rock canyons and quiet forests, it’s ideal for meditation, yoga, and personal reflection. Guests can book healing sessions, guided hikes, and gourmet plant-based meals. With sustainability at its core, the sanctuary is built to harmonize with nature. It’s a place to unplug, reset, and realign. Whether you’re on a wellness journey or simply need a break from the noise, this vacation rental offers deep rest and inspiration.
#11 Lake Havasu City
Lake Havasu City is a water-lover’s paradise in the Arizona desert. Best known for the relocated London Bridge and its expansive lake, it’s the go-to spot for boating, paddleboarding, and lakeside lounging. The city has a festive vibe, especially during spring and summer, with waterfront restaurants, bars, and sandy beaches. Visitors can explore island trails, rent jet skis, or take scenic boat tours. It’s also a family-friendly spot with parks and picnic areas. With 300 days of sunshine a year, Lake Havasu offers a fun, sun-soaked Arizona getaway.
#12 Monument Valley
Monument Valley’s dramatic sandstone buttes are an iconic symbol of the American West. Located within the Navajo Nation, the area’s beauty and spiritual presence are unforgettable. Visitors can take guided tours through the sacred landscape, often led by Navajo guides sharing the area’s deep cultural history. The sunrise and sunset views here are otherworldly, casting long shadows and golden hues across the desert floor. This is one of the most photographed places on earth—and it lives up to the hype. Monument Valley is a must-see for anyone traveling through northern Arizona.
Conclusion:
Arizona offers more than just beautiful views—it’s a state full of soul, story, and unforgettable stays. From Sedona’s spiritual energy to Scottsdale’s cosmopolitan flair, each destination has its own unique charm and incredible vacation rentals to match. Whether you’re hiking through slot canyons, exploring ghost towns, or soaking up sunset views with wine in hand, Arizona invites you to slow down, breathe deep, and truly connect. With so many welcoming homes and one-of-a-kind stays, your adventure doesn’t end when the day is done—it just begins a new chapter. Let Arizona’s magic guide your next unforgettable journey.
